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Most posts on chronic fatigue syndrome, fibromyalgia & hypersensitivities are on my blog www.cfsfmmcschirps.Tumblr.com
All other illnesses are on this blog.
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New Test for Kidney Function:
Traditionally, doctors have used markers such as creatine to measure kidney damage. This study found, Cystatin C,” … is a novel serum marker for kidney disease that may better detect small changes in kidney function.” It,”may be superior in detecting an association with inflammation in subjects with mild to moderate kidney disease… ” (Keller et al.)
Most patients are diagnosed with common variable immune deficiency (CVID) between the ages of 20 and 40 years; however, the diagnosis commonly is delayed by 6 to 8 years, even after the onset of characteristic symptoms.
CVID: Liver disease… which may lead to persistently increased liver enzyme levels, also occurs in CVID.… In one cohort study, 43% of patients had abnormal liver function tests, predominantly increased alkaline phosphatase.
CVID: Reviews from the 1970s to the present have noted a high incidence of GI manifestations in CVID, ranging from 20% to 60% of patients. Many of these GI manifestations mimic … pernicious anemia, sprue-like lesions (celiac), and IBD but the pathology is not comparable …
Review of Immune Deficiencies - Section on Common Variable immune Deficiency (CVID)
GI/Liver Involvement & Medicines . .
"Patients report symptoms of bloating, diarrhea, and weight loss."
"In the stomach, Helicobacter pylori infection has been associated with gastritis. Atrophic gastritis, which resembles autoimmune gastritis developing into pernicious anemia, may occur in the absence of demonstrable antiparietal cell antibodies in CVID patients."
"Small-bowel pathology is similar to what is seen in classic celiac sprue … Unlike the patients with celiac sprue … the affected patients do not make antibodies to tissue transglutaminase, endomysium, or gliadin. Affected CVID patients typically do not respond to gluten withdrawal … "
"Liver disease, including primary biliary cirrhosis and autoimmune hepatitis, which may lead to persistently increased liver enzyme levels, also occurs in CVID. The cause remains unknown… In one cohort study, 43% of patients had abnormal liver function tests, predominantly increased alkaline phosphatase."
"Similar to other antibody deficiency disorders, G lambliais the most common organism found, although other pathogens such as C parvum, cytomegalovirus, Salmonella species, and Campylobacter jejuni have been reported."
"Patients are treated with monthly infusions of IgG; this treatment alone may not be effective in treating other manifestations of this disorder."
This review also discusses medicines and cautions,”Corticosteroids at any dose can lead to a significant risk of infections.” “Although the inflammatory process responds to steroid therapy, prolonged therapy with steroids is not advisable in CVID patients.” (Agarwal & Mayer)
In most studies, women report more severe levels of pain, more frequent pain and pain of longer duration than do men. Women may be at greater risk for pain-related disability than men … Women may be more vulnerable than men to unwarranted psychogenic attributions by health care providers for pain.
… at least 79% of animal studies published in Pain over the preceding 10 years included male subjects only, with a mere 8% of studies on females only, and another 4% explicitly designed to test for sex differences. Given the substantially greater prevalence of many clinical pain conditions in women vs. men and growing evidence for sex differences in sensitivity to experimental pain and to analgesics, we recommend that all pain researchers consider testing their hypotheses in both sexes, or if restricted by practical considerations, only in females.
Bipolar: There is evidence to suggest that young onset mania is triggered more often by stress than adult onset.
A popular myth in psychiatry was that bipolar disorder is easily recognisable with clear episodes of mania and depression interspersed with lengthy periods of normal functioning. And that even when it onsets in children and adolescents it is straightforward to diagnose and can be treated with the same concoction of mood stabilizers and antipsychotics that “cures or controls” adults with bipolar disorder (BD). This myth has been decimated by the mountain of literature that has accumulated on paediatric bipolar disorder (PBD) over the last two decades.